I don't always care for the mix of horror and humor. I tried watching the Return of the Living Dead movies and they just didn't appeal to me. However one one movie combining these two elements that is so much fun to watch is Shaun of the Dead.
I'm not sure if it's the British wit that makes this so great, but Simon Pegg and Nick Frost are absolutely hilarious in this movie. Great story and special effects to top things off. I'm looking forward to dusting off my HD DVD version and plopping down on the couch for this one!